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The results indicated that in spite of sildenafil being more expensive than beraprost, generic sildenafil could potentially be a good value for money since ICER per QALY is below one times gross domestic product GDP per capita in Indonesia. PAH is a progressive disease, ultimately leading to right heart failure and death 5. The etiologies of PAH are unknown or idiopathic, familial, or associated with certain diseases, such as congenital heart disease, connective tissue disease, portal hypertension, and HIV sildenafil 5 price, or exposure to toxins and drugs including appetite suppressant drugs 6. The World Health Organization WHO classifies PAH according to symptoms experienced by patients, including shortness of breath, fatigue, chest pain, syncope, and limitation of physical activities. Establishing a PAH diagnosis is problematic because patients are usually unaware of the disease symptoms, making it difficult to estimate the number of PAH cases 1.

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