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Below find: January brand medication cost increases, first-time generic releases and expected generic launches. Although the medications listed below do not have FDA-approved generics, cost-effective therapeutic alternatives may be available. Keep in mind that some of these new generic medications continue to have very high prices per unit, and most have more cost-effective therapeutic alternatives available. Note that prospective generic launch dates are subject to change depending on factors beyond our control. As with the newly available generics, most of these products also have more cost-effective therapeutic alternatives available. Optum constantly monitors trends in the marketplace pertaining to generic availability of brand-name medications and AWP changes that may positively or negatively affect WCMSAs.

Current strategies to mitigate the opioid crisis and manage chronic pain focus on new products that treat pain effectively with lower potential for abuse and addiction. A Schedule II centrally acting opioid analgesic, tapentadol has two proposed mechanisms of action—mu-opioid agonist activity and norepinephrine reuptake inhibition. Tapentadol modulates pain signals in both ascending and descending neural pathways. Broader post-marketing data sources, including surveillance results from nationwide programs dedicated to studying and preventing addiction, pharmacy and medical claims databases, and online discussion forums have become available over the past decade as well. In addition, intentional exposure rates for tapentadol IR were low, ranging from 0.

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