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Premarin vaginal cream is considered a conjugated estrogens cream, which contains a mixture of estrogen hormones. Conjugated estrogens help treat changes in and around the vagina, such as dryness, itching, and burning in postmenopausal women. It can also help treat vaginal pain during sexual intercourse. There is 1 FDA-approved use for Premarin vaginal cream, but your healthcare provider may also prescribe it off-label to treat other medical conditions. Some common uses of Premarin vaginal cream include

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