Promethazine hydrochloride is a type of drowsy antihistamine that is commonly used to help people with sleeping problems. It can help to treat motion sickness and cold symptoms like a runny nose too. It helps many people of all ages treat their insomnia or difficulties getting to sleep. Histamine is a chemical released into the brain when you have an allergic reaction. Yet it also plays a different role. While the hormone melatonin makes you want to go to sleep, histamine wakes you up. As an anti histamine, promethazine blocks the effect of this chemical.

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