The largest countrywide epidemiologic study was done in France, revealing that candidemia, Pneumocystis jirovecii pneumonia, invasive aspergillosis, cryptococcosis, and mucormycosis were the top 5 IFIs admitted. While invasive pulmonary aspergillosis is the most devastating of IFIs, the most common IFI is candidemia presence of Candida yeasts in the peripheral blood. It is the most common manifestation of invasive candidiasis which can be caused by many different species of Candida including C. In addition, patients who are immunocompromised due to cancer chemotherapy or transplantation are also at risk of Candida bloodstream infections. These infections are usually diagnosed by blood cultures but there are some novel diagnostics on the horizon. Treatment Options Systemic antifungal agents available for the treatment of various types of candidiasis comprise of 4 major therapeutic classes, i.

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