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Baclofen, a gamma-aminobutyric acid B GABA B agonist, controls withdrawal symptoms without causing significant adverse effects. This was a randomized, open label, standard controlled, parallel group study of cost-effectiveness analysis CEA of baclofen and chlordiazepoxide in 60 prices of baclofen 30 mg with uncomplicated AWS. Lorazepam was used as supplement medication if withdrawal symptoms could not be controlled effectively by the study drugs alone. The average cost-effectiveness ratio ACER in patient's perspective of baclofen and chlordiazepoxide was Rs. Both study drugs provided relief of withdrawal symptoms. Chlordiazepoxide was more cost-effective than baclofen.

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